Selected article for: "PCR amplification and wild type"

Author: Roquebert, Benedicte; Haim-Boukobza, Stéphanie; Trombert-Paolantoni, Sabine; Lecorche, Emmanuel; Verdurme, Laura; Foulongne, Vincent; Burrel, Sonia; Alizon, Samuel; Sofonea, Mircea T.
Title: SARS-CoV-2 variants of concern are associated with lower RT-PCR amplification cycles between January and March 2021 in France
  • Cord-id: 89nbij6t
  • Document date: 2021_10_1
  • ID: 89nbij6t
    Snippet: SARS-CoV-2 variants raise concern regarding the mortality caused by COVID-19 epidemics. We analyse 88,375 cycle amplification (Ct) values from variant-specific RT-PCR tests performed between January 26 and March 13, 2021. We estimate that on March 12, nearly 85% of the infections were caused by the Alpha variant and that its transmission advantage over wild type strains was between 38 and 44%. We also find that tests positive for Alpha and Beta/Gamma variants exhibit significantly lower cycle th
    Document: SARS-CoV-2 variants raise concern regarding the mortality caused by COVID-19 epidemics. We analyse 88,375 cycle amplification (Ct) values from variant-specific RT-PCR tests performed between January 26 and March 13, 2021. We estimate that on March 12, nearly 85% of the infections were caused by the Alpha variant and that its transmission advantage over wild type strains was between 38 and 44%. We also find that tests positive for Alpha and Beta/Gamma variants exhibit significantly lower cycle threshold (Ct) values.

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