Selected article for: "hemolytic anemia and severe hemolytic anemia"
Author: Sardar, Sundus; Abdurabu, Mohammed; Abdelhadi, Ahmed; Habib, Mhd Baraa; Jamshaid, Muhammad Bilal; Hajjar, Adnan Humam; Abu Ageila, Munir; Abdalla, Tasnim; Kartha, Anand; Farooqui, Khalid
Title: Artesunate-induced hemolysis in severe complicated malaria – A diagnostic challenge: A case report and literature review of anemia in malaria
  • Cord-id: 9p22ob6x
  • Document date: 2021_7_24
    • ID: 9p22ob6x
    Snippet: Malaria infection, which results due to the parasitic protozoan Plasmodium, has several known etiologies of hemolytic anemia as a possible complication in cases such as concurrent G6PD deficiency, severe parasitemia, or use of parenteral antimalarials. Although artemisinin-based antimalarial therapies are generally well-tolerated, several cases of severe post-artemisinin delayed hemolysis (PADH) have been recently reported, which present a diagnostic challenge, and affect morbidity and mortality
    Document: Malaria infection, which results due to the parasitic protozoan Plasmodium, has several known etiologies of hemolytic anemia as a possible complication in cases such as concurrent G6PD deficiency, severe parasitemia, or use of parenteral antimalarials. Although artemisinin-based antimalarial therapies are generally well-tolerated, several cases of severe post-artemisinin delayed hemolysis (PADH) have been recently reported, which present a diagnostic challenge, and affect morbidity and mortality in patients with malarial infection. We highlight the case of a young lady with Plasmodium falciparum severe parasitemia who developed hemolytic anemia after parenteral artesunate therapy.

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