Author: Wu, Yi-Feng; Yu, Wan-Jun; Jiang, Yu-Hua; Chen, Yin; Zhang, Bo; Zhen, Rui-Bing; Zhang, Jun-Tao; Wang, Yi-Ping; Li, Qiang; Xu, Feng; Shi, Yan-Jun; Li, Xian-Peng
Title: COVID-19 or treatment associated immunosuppression may trigger hepatitis B virus reactivation: A case report Cord-id: 3wvjyhux Document date: 2021_7_6
ID: 3wvjyhux
Snippet: BACKGROUND: Since the initial recognition of coronavirus disease 2019 (COVID-19) in Wuhan, this infectious disease has spread to most areas of the world. The pathogenesis of COVID-19 is yet unclear. Hepatitis B virus (HBV) reactivation occurring in COVID-19 patients has not yet been reported. CASE SUMMARY: A 45-year-old hepatitis B man with long-term use of adefovir dipivoxil and entecavir for antiviral therapy had HBV reactivation after being treated with methylprednisolone for COVID-19 for 6 d
Document: BACKGROUND: Since the initial recognition of coronavirus disease 2019 (COVID-19) in Wuhan, this infectious disease has spread to most areas of the world. The pathogenesis of COVID-19 is yet unclear. Hepatitis B virus (HBV) reactivation occurring in COVID-19 patients has not yet been reported. CASE SUMMARY: A 45-year-old hepatitis B man with long-term use of adefovir dipivoxil and entecavir for antiviral therapy had HBV reactivation after being treated with methylprednisolone for COVID-19 for 6 d. CONCLUSION: COVID-19 or treatment associated immunosuppression may trigger HBV reactivation.
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