Author: Xavier Hernandez-Alias; Martin Schaefer; Luis Serrano
Title: Translational adaptation of human viruses to the tissues they infect Document date: 2020_4_7
ID: 0rk2dw4e_15
Snippet: Overall, as tropism of proteins can be predicted from their translational adaptation to tissues, these results indicate that viral proteomes are specifically adapted to certain tRNA-based translational efficiencies. In consequence, and complementary to the observations of mutational pressure driving viral codon bias 11, 29, 30 , we describe the basis for a potential tissuespecific translational selection of the viral codon usage......
Document: Overall, as tropism of proteins can be predicted from their translational adaptation to tissues, these results indicate that viral proteomes are specifically adapted to certain tRNA-based translational efficiencies. In consequence, and complementary to the observations of mutational pressure driving viral codon bias 11, 29, 30 , we describe the basis for a potential tissuespecific translational selection of the viral codon usage.
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