A case of SARS‐CoV‐2 infection in an untreated HIV patient in Tokyo, Japan

Nakamoto, Takato; Kutsuna, Satoshi; Yanagawa, Yasuaki; Kanda, Kouhei; Okuhama, Ayako; Akiyama, Yutaro; Miyazato, Yusuke; Ide, Satoshi; Nakamura, Keiji; Yamamoto, Kei; Ohmagari, Norio

We report a 28‐year‐old male co‐infected with SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2; COVID‐19) and human immunodeficiency virus (HIV). His clinical course of the COVID‐19 pneumonia improved smoothly in 9 days; however, his immune status from HIV infection was not well‐controlled due to a lack of antiretroviral therapy (ART). The HIV‐1 viral load decreased during the acute phase and subsequently increased in the recovery phase. Antiretroviral therapy was given a month after the twice non‐detections of SARS‐CoV‐2 to avoid immune reconstitution syndrome (IRIS). Previous reports suggest COVID‐19 do not become more severe in untreated HIV patients than non‐HIV patients. However, untreated HIV patients with COVID‐19 should be followed up carefully for IRIS with ART. This article is protected by copyright. All rights reserved.