Selected article for: "cytokine storm and host defense"
Author: Chang, Feng-Yee; Chen, Hsiang-Cheng; Chen, Pei-Jer; Ho, Mei-Shang; Hsieh, Shie-Liang; Lin, Jung-Chung; Liu, Fu-Tong; Sytwu, Huey-Kang
Title: Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19)
  • Cord-id: 9vechh4x
  • Document date: 2020_6_4
    • ID: 9vechh4x
    Snippet: On March 11, 2020, the World Health Organization declared the worldwide spread of the infectious disease COVID-19, caused by a new strain of coronavirus, SARS-CoV-2, as a pandemic. Like in all other infectious diseases, the host immune system plays a key role in our defense against SARS-CoV-2 infection. However, viruses are able to evade the immune attack and proliferate and, in susceptible individuals, cause severe inflammatory response known as cytokine storm, particularly in the lungs. The ad
    Document: On March 11, 2020, the World Health Organization declared the worldwide spread of the infectious disease COVID-19, caused by a new strain of coronavirus, SARS-CoV-2, as a pandemic. Like in all other infectious diseases, the host immune system plays a key role in our defense against SARS-CoV-2 infection. However, viruses are able to evade the immune attack and proliferate and, in susceptible individuals, cause severe inflammatory response known as cytokine storm, particularly in the lungs. The advancement in our understanding of the mechanisms underlying the host immune responses promises to facilitate the development of approaches for prevention or treatment of diseases. Components of immune system, such as antibodies, can also be used to develop sensitive and specific diagnostic methods as well as novel therapeutic agents. In this review, we summarize our knowledge about how the host mounts immune responses to infection by SARS-CoV-2. We also describe the diagnostic methods being used for COVID-19 identification and summarize the current status of various therapeutic strategies, including vaccination, being considered for treatment of the disease.

    Search related documents:
    Co phrase search for related documents
    • abortive infection and acute infection: 1, 2, 3, 4, 5
    • abortive infection and acute respiratory syndrome: 1, 2, 3, 4, 5
    • abortive infection and acute viral infection: 1
    • acid receptor and acute ards respiratory distress syndrome: 1
    • acid receptor and acute infection: 1, 2, 3, 4, 5
    • acid receptor and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acid receptor and adaptive immune response: 1
    • acid vaccine and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • acute ards respiratory distress syndrome and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • acute ards respiratory distress syndrome and additional file: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • acute ards respiratory distress syndrome include and additional file: 1
    • acute infection and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute infection and additional file: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • acute mild and adaptive immune response: 1, 2, 3, 4
    • acute mild respiratory syndrome and adaptive immune response: 1, 2, 3
    • acute respiratory syndrome and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute respiratory syndrome and additional file: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute viral infection and adaptive immune response: 1, 2, 3, 4
    • adaptive immune response and additional file: 1