Author: David M Rubin; Neil T Stacey; Tonderayi Matambo; Diane Hildebrandt
Title: Oxygen transfer characteristics of a hollow fiber dialyser: toward possible repurposing of dialysers as blood oxygenators in the context of constrained availability of respiratory support Document date: 2020_4_11
ID: 4igpae7w_38
Snippet: For the likely latter scenario of a 0.1 kP a partial pressure drop for the pO bottom 2 , and substituting into equation [2] together with the minimum oxygen transfer rate of from the water experiments of 14.6 mg/min, the kA value is 1.334 g/(min · kP A) which will produce an oxygen mass transfer rate that is 3.4 fold larger than required to fully oxygenate the blood to 95 % saturation if the incoming pO2 is 45 mmHg, and 1.7 fold larger than need.....
Document: For the likely latter scenario of a 0.1 kP a partial pressure drop for the pO bottom 2 , and substituting into equation [2] together with the minimum oxygen transfer rate of from the water experiments of 14.6 mg/min, the kA value is 1.334 g/(min · kP A) which will produce an oxygen mass transfer rate that is 3.4 fold larger than required to fully oxygenate the blood to 95 % saturation if the incoming pO2 is 45 mmHg, and 1.7 fold larger than needed if the incoming pO2 is 25 mmHg. Even if we assume the unlikely case of a pO bottom 2 of 6 kP A, the potential mass transfer rate of oxygen will be 1.4 fold larger than the minimum needed for incoming blood with oxygen partial pressure of 45 mmHg and 70% of the required amount for an incoming saturation of 25 mmHg.
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