Author: Divya RSJB Rana; Santosh Dulal
Title: Therapeutic Application of Chloroquine in Clinical Trials for COVID-19 Document date: 2020_3_27
ID: jc9ugexn_3
Snippet: The recommended 3-day chloroquine phosphate dosage for malaria treatments for adults is 1 gm orally followed by 500 mg after 6-8 hours in the first day and 500 mg per day for second and the third day (8) . Similarly, the 3-day dosage for hydroxychloroquine is 800 mg orally followed by 400 mg after 6-8 hours in the first day and 400 mg per day for second and third day (11) . This study was specifically conducted to examine the various dosages of c.....
Document: The recommended 3-day chloroquine phosphate dosage for malaria treatments for adults is 1 gm orally followed by 500 mg after 6-8 hours in the first day and 500 mg per day for second and the third day (8) . Similarly, the 3-day dosage for hydroxychloroquine is 800 mg orally followed by 400 mg after 6-8 hours in the first day and 400 mg per day for second and third day (11) . This study was specifically conducted to examine the various dosages of chloroquine and hydroxychloroquine utilized in previous clinical trials registered and underwent for the treatment of pneumonia caused by SARS-CoV-2. The guidelines by the Chinese government has postulated the dose of 500 mg twice a day for 7 days for adults aged 18-65 years and weighing more than 50 kg; and initial dose of 500 mg twice a day for first two days and 500 mg per day for days 3 through 7 for adults of weight less than 50 kg (7).
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