Utah-Stanford Ventilator (Vent4US): Developing a rapidly scalable ventilator for COVID-19 patients with ARDS

Hongquan Li; Ethan Li; Deepak Krishnamurthy; Patrick Kolbay; Beca Chacin; Soeren Hoehne; Jim Cybulski; Lara Brewer; Tomasz Petelenz; Joseph Orr; Derek Sakata; Thomas Clardy; Kai Kuck; Manu Prakash

Depletion of internal backup power reserves for alarms below 50% of full capacity. c. Other detectable failures of software or hardware subsystems or components. 6. Biological safety of all components in contact with breathing gases. 7. Infection control to prevent nosocomial infections: a. Disposability or decontaminability of all parts which come into contact with the patient's breath. b. Impermeable casing around all working components of the device. c. Easy cleaning of all external surfaces after exposure to respiratory secretions or blood splatter. d. Pressure delivered must account for any pressure drop from an HME viral filter placed in-line on the endotracheal tube between the system and the patient. e. Controllable "stand-by" or "switch-off" functionality to stop flow during disconnection of ETT without aerosolization. 8. Reliability: a. Continuous ventilation at 100% duty cycle for 14 days without any subsystem or component failures and without servicing or replacement of any subsystems or components. b. Continuous operation without subsystem/component failures resulting from mechanical shocks and vibrations as encountered during regular patient transfer within a medical facility. c. Fast and easy servicing and replacement of subsystems/components to minimize downtime. 9. Ease of use: