Selected article for: "expression similarity and gene expression"
Author: Héctor Cervera; Silvia Ambrós; Guillermo P. Bernet; Guillermo Rodrigo; Santiago F. Elena
Title: Viral fitness predicts the magnitude and direction of perturbations in the infected host transcriptome
  • Document date: 2017_10_20
    • ID: 0qmsripp_11
    Snippet: Next, to further investigate the similarity between expression profiles of plants infected with different TEV genotypes, we performed principal components analysis (PCA) of all the gene expression data. The percentage of total observed variance explained by the first three PCAs was ~93% (the first principal component, pc 1 , itself explained up to 81%). Fig. 3C shows the distribution of values in the space defined by the three first principal com.....
    Document: Next, to further investigate the similarity between expression profiles of plants infected with different TEV genotypes, we performed principal components analysis (PCA) of all the gene expression data. The percentage of total observed variance explained by the first three PCAs was ~93% (the first principal component, pc 1 , itself explained up to 81%). Fig. 3C shows the distribution of values in the space defined by the three first principal components. Results are equivalent to those obtained with the two previous clustering methods, as genotypes are classified into three groups. WT, PC55 and PC48 are closer in the space and characterized by positive values of pc 1 but negative values of the second (pc 2 ) and third (pc 3 ) components. CLA11, PC95 and CLA2 form a second group, with positive values of pc 1 and pc 2 but negative values of pc 3 .

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