Author: Alejandro A Schäffer; Eneida Hatcher; Linda Yankie; Lara Shonkwiler; J Rodney Brister; Ilene Karsch-Mizrachi; Eric P Nawrocki
Title: VADR: validation and annotation of virus sequence submissions to GenBank Document date: 2019_11_22
ID: besvz92f_71
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/852657 doi: bioRxiv preprint the correctness of their annotation. In our testing of VADR since May 2018, indexers have manually reviewed the sequences that pass VADR and have largely agreed that they should indeed pass. Where they have disagreed, we have modified VADR during its development to fail the sequences in question. Additi.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/852657 doi: bioRxiv preprint the correctness of their annotation. In our testing of VADR since May 2018, indexers have manually reviewed the sequences that pass VADR and have largely agreed that they should indeed pass. Where they have disagreed, we have modified VADR during its development to fail the sequences in question. Additionally, in our testing of the NP and NC datasets, when VADR and VIGOR both pass a sequence they nearly always have the same annotations: 703 of the 705 (99.7%) of the CDS annotations with consistent product names (VP1, VP2 or nonstructural polyprotein) had identical coordinates in the VADR and VIGOR output.
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