Author: A.J.W. Haasnoot; M.W. Schilham; S.S.M. Kamphuis; P.C.E. Hissink Muller; A. Heiligenhaus; D. Foell; R.A. Ophoff; T.R.D.J. Radstake; A.I. Den Hollander; T.H.C.M. Reinards; S. Hiddingh; N. Schalij-Delfos; E.P.A.H. Hoppenreijs; M.A.J. van Rossum; C. Wouters; R.K. Saurenmann; N. Wulffraat; R. ten Cate; J.H. de Boer; S.L. Pulit; J.J.W. Kuiper
Title: An amino acid motif in HLA-DRß1 distinguishes patients with uveitis in juvenile idiopathic arthritis Document date: 2017_5_22
ID: 4it5c9n2_16
Snippet: To further explore the potential for a sex-specific effect at HLA-DRB1 position 11, we ran the association test at serine-11 across all samples, including an interaction term between sex and the imputed dosage at serine-11. We found a significant effect of the interaction term (OR = 2.25 [95% CI: 1.22-4.15] p = 0.0096), indicating that the serine-11 signal in HLA-DRB1 was indeed a sex-specific effect......
Document: To further explore the potential for a sex-specific effect at HLA-DRB1 position 11, we ran the association test at serine-11 across all samples, including an interaction term between sex and the imputed dosage at serine-11. We found a significant effect of the interaction term (OR = 2.25 [95% CI: 1.22-4.15] p = 0.0096), indicating that the serine-11 signal in HLA-DRB1 was indeed a sex-specific effect.
Search related documents:
Co phrase search for related documents- association test and HLA DRB1 signal: 1
- association test and significant effect: 1, 2
- interaction term and significant effect: 1
Co phrase search for related documents, hyperlinks ordered by date