Author: Yujia Xiang; Quan Zou; Lilin Zhao
Title: VPTMdb: a viral post-translational modification database Document date: 2020_4_2
ID: kl99afiu_65
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.01.019562 doi: bioRxiv preprint classifiers' performance from the 5-fold cross validation (Supplementary Table S3 ). Figure 3A shows that the maximum AUCs of the svm and random forest are similar. For the random forest and svm, the AUCs increased when more features were selected (random forest: 14-135 features, with AUC > 0.90; svm: 27-13.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.01.019562 doi: bioRxiv preprint classifiers' performance from the 5-fold cross validation (Supplementary Table S3 ). Figure 3A shows that the maximum AUCs of the svm and random forest are similar. For the random forest and svm, the AUCs increased when more features were selected (random forest: 14-135 features, with AUC > 0.90; svm: 27-135 features, with AUC > 0.90). However, we observed that the AUCs of naïve Bayes (AUCs > 0.80) decreased when more features were added. From a statistical point of view, to prevent the curse of dimensionality, fewer and more meaningful features should be chosen. Taking the above results into consideration, for 68 features, the AUCs of the three predictors perform better, suggesting that 68D is the most meaningful feature among all the features.
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