Author: Green, Cameron M.; Fanucchi, Stephanie; Fok, Ezio T.; Moorlag, Simone J.C.F.M.; Dominguez-Andres, Jorge; Negishi, Yutaka; Joosten, Leo A.B.; Netea, Mihai G.; Mhlanga, Musa M.
ID: i38nmjxu
Snippet: We use a data quality model to demonstrate that BCG vaccination is correlated with protection from death from COVID19. From a mechanistic perspective, BCG is well described to elicit its protective non-specific effects through the process of trained immunity. Therapeutically enhancing trained immunity may therefore be an important mechanism in protection from the lethal effects of COVID19
Document: We use a data quality model to demonstrate that BCG vaccination is correlated with protection from death from COVID19. From a mechanistic perspective, BCG is well described to elicit its protective non-specific effects through the process of trained immunity. Therapeutically enhancing trained immunity may therefore be an important mechanism in protection from the lethal effects of COVID19
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