Author: Sha Fu; Xiaoyu Fu; Yang Song; Min Li; Pin-hua Pan; Tao Tang; Chunhu Zhang; Tiejian Jiang; Deming Tan; Xuegong Fan; Xinping Sha; Jingdong Ma; Yan Huang; Shaling Li; Yixiang Zheng; Zhaoxin Qian; Zeng Xiong; Lizhi Xiao; Huibao Long; Jianghai Chen; Yi Ouyang
Title: Virologic and clinical characteristics for prognosis of severe COVID-19: a retrospective observational study in Wuhan, China Document date: 2020_4_6
ID: 4989atst_32
Snippet: It was found that clinical recovery of patients typically occurred with viral clearing in patients with good recovery. However, it was also found that viral shedding could persist for an interval of few days, despite clinical improvements. Although Zhou et al. reported out that the median duration of viral shedding was 20.0 days (IQR, 17-24 days) in survivors of COVID-19 16 , the duration of viral shedding was found to be greatly extended in this.....
Document: It was found that clinical recovery of patients typically occurred with viral clearing in patients with good recovery. However, it was also found that viral shedding could persist for an interval of few days, despite clinical improvements. Although Zhou et al. reported out that the median duration of viral shedding was 20.0 days (IQR, 17-24 days) in survivors of COVID-19 16 , the duration of viral shedding was found to be greatly extended in this present study, with a median duration of 31 days after symptom onset (IQR, 27-34 days). This difference might be due to specimen collection, disease severity, immunological response, corticosteroid usage, antiviral treatments, and the duration of the observational window in these various populations.
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