Author: Daniel Bean; Zeljko Kraljevic; Thomas Searle; Rebecca Bendayan; Andrew Pickles; Amos Folarin; Lukasz Roguski; Kawsar Noor; Anthony Shek; Kevin o'gallagher; Rosita Zakeri; Ajay Shah; James Teo; Richard JB Dobson
Title: Treatment with ACE-inhibitors is associated with less severe disease with SARS-Covid-19 infection in a multi-site UK acute Hospital Trust Document date: 2020_4_11
ID: 60wcvkbn_18
Snippet: This study suggests that ACE-inhibitors do not increase the severity of COVID-19 disease as hypothesised 4-7 but may reduce severity. This holds true even after adjusting for conditions where ACEi may be used (hypertension, diabetes mellitus, ischaemic heart disease and heart failure). No meaningful comment can be made about ARB effect given the low prevalence of their use in this cohort, although ARB have a different mechanism of action compared.....
Document: This study suggests that ACE-inhibitors do not increase the severity of COVID-19 disease as hypothesised 4-7 but may reduce severity. This holds true even after adjusting for conditions where ACEi may be used (hypertension, diabetes mellitus, ischaemic heart disease and heart failure). No meaningful comment can be made about ARB effect given the low prevalence of their use in this cohort, although ARB have a different mechanism of action compared to ACEi.
Search related documents:
Co phrase search for related documents- disease severity and heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- disease severity and heart failure: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- disease severity and heart failure ischaemic heart disease: 1
- disease severity and ischaemic heart disease: 1
- disease severity and low prevalence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- disease severity and severity reduce: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- disease severity and true hold: 1
- disease severity increase and heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9
- disease severity increase and heart failure: 1, 2, 3, 4, 5, 6, 7
- disease severity increase and severity reduce: 1, 2
- heart disease and ischaemic heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- heart disease and low prevalence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- heart disease and severity reduce: 1, 2, 3, 4, 5
- heart failure and ischaemic heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- heart failure and low prevalence: 1, 2, 3, 4, 5, 6, 7, 8, 9
- heart failure and severity reduce: 1
- heart failure ischaemic heart disease and ischaemic heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- ischaemic heart disease and low prevalence: 1, 2
- low prevalence and severity reduce: 1, 2
Co phrase search for related documents, hyperlinks ordered by date