Selected article for: "disease severity and presentation disease severity variation"

Author: Jacobs, Merel; Lahousse, Lies; Van Eeckhoutte, Hannelore P.; Wijnant, Sara R.A.; Delanghe, Joris R.; Brusselle, Guy G.; Bracke, Ken R.
Title: Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
  • Cord-id: b3pi0ssq
  • Document date: 2021_2_25
  • ID: b3pi0ssq
    Snippet: Coronavirus Disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently invoking a pandemic with a huge medical and financial impact. One of the striking features of this pandemic is the considerable variation in disease presentation and severity amongst patients, ethnic groups, and countries. This variation can be partially explained by differences in population density, demographic factors (age, sex) and comorbidities (e.g. hypertension, obesity a
    Document: Coronavirus Disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently invoking a pandemic with a huge medical and financial impact. One of the striking features of this pandemic is the considerable variation in disease presentation and severity amongst patients, ethnic groups, and countries. This variation can be partially explained by differences in population density, demographic factors (age, sex) and comorbidities (e.g. hypertension, obesity and diabetes mellitus). Also genetic factors likely contribute to SARS-CoV-2 infection risk and/or COVID-19 development.

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