Author: Cao, L.; Zhao, S.; Lou, J.; Zheng, H.; Mok, C. K. P.; Chan, R. W.; Chong, K. C.; Chen, Z.; Chan, P. K.; Zee, B. C.-Y.; Wang, M. H.
Title: Genetic mismatch explains sizable variation of COVID-19 vaccine efficacy in clinical trials Cord-id: avf1n9uj Document date: 2021_4_22
ID: avf1n9uj
Snippet: Pulling vaccine efficacy and effectiveness (VE) outcomes from 17 reports of 9 different vaccine products and through sequence analysis, we found that genetic mismatch explained sizable variations in VE. The findings suggested the potential need of timely optimizing vaccine antigens as new dominant viral strains emerge.
Document: Pulling vaccine efficacy and effectiveness (VE) outcomes from 17 reports of 9 different vaccine products and through sequence analysis, we found that genetic mismatch explained sizable variations in VE. The findings suggested the potential need of timely optimizing vaccine antigens as new dominant viral strains emerge.
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