Author: Gong, Yuan; Guan, Li; Jin, Zhu; Chen, Shixiong; Xiang, Guangming; Gao, Baoan
Title: Effects of methylprednisolone use on viral genomic nucleic acid negative conversion and CT imaging lesion absorption in COVIDâ€19 patients under 50 years old Cord-id: jx1ws18b Document date: 2020_5_22
ID: jx1ws18b
Snippet: The use of corticosteroids has been controversial in viral pneumonia. In most cases, application of methylprednisolone in severe and critical viral pneumonia patients can quickly alleviate the symptoms of dyspnea and prevent disease progression. However, some scholars have confirmed that corticosteroids delayed the body's clearance of the virus. In our retrospective nonâ€randomised study, 34 patients under 50 years old and diagnosed with coronavirus disease 2019 (COVIDâ€19) were included, acco
Document: The use of corticosteroids has been controversial in viral pneumonia. In most cases, application of methylprednisolone in severe and critical viral pneumonia patients can quickly alleviate the symptoms of dyspnea and prevent disease progression. However, some scholars have confirmed that corticosteroids delayed the body's clearance of the virus. In our retrospective nonâ€randomised study, 34 patients under 50 years old and diagnosed with coronavirus disease 2019 (COVIDâ€19) were included, according to given methylprednisolone treatment (n = 18) or not (n = 16), they were separated into 2 groups. By comparing the clinical data we concluded that corticosteroids therapy can effectively release COVIDâ€19 symptoms such as persistent fever and difficult breathing, improve oxygenation and prevent disease progression. However, it can prolong the negative conversion of nucleic acids. This article is protected by copyright. All rights reserved.
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