Author: Varese, Augusto; Ceballos, Ana; Palacios, Carlos; Figueroa, Juan Manuel; Dugour, Andrea Vanesa
Title: Iota-carrageenan prevents the replication of SARS-CoV-2 on an in vitro respiratory epithelium model Cord-id: 9fjm9rqv Document date: 2021_4_27
ID: 9fjm9rqv
Snippet: There are, except for remdesivir, no approved antivirals for the treatment or prevention of SARS-CoV-2 infections. Iota-carrageenan formulated into a nasal spray has already been proven safe and effective in viral respiratory infections. We explored this antiviral activity in Calu-3, a human respiratory model cell line. A formula of iota-carrageenan and sodium chloride, as a nasal spray, already approved for human use, effectively inhibited SARS-CoV-2 infection in vitro, providing a more substan
Document: There are, except for remdesivir, no approved antivirals for the treatment or prevention of SARS-CoV-2 infections. Iota-carrageenan formulated into a nasal spray has already been proven safe and effective in viral respiratory infections. We explored this antiviral activity in Calu-3, a human respiratory model cell line. A formula of iota-carrageenan and sodium chloride, as a nasal spray, already approved for human use, effectively inhibited SARS-CoV-2 infection in vitro, providing a more substantial reference for further clinical studies or developments.
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