Author: Estefania Nunez-Bajo; Michael Kasimatis; Yasin Cotur; Tarek Asfour; Alex Collins; Ugur Tanriverdi; Max Grell; Matti Kaisti; Guglielmo Senesi; Karen Stevenson; Firat Guder
Title: Ultra-Low-Cost Integrated Silicon-based Transducer for On-Site, Genetic Detection of Pathogens Document date: 2020_3_25
ID: 7a3wdduq_15
Snippet: NA amplification reactions require maintaining the sample at a temperature setpoint with high °precision. For PCR, the duration of each heating step must also be carefully controlled. Because the TriSilix uses Si, the substrate itself can be used both as an electrical heater and temperature sensor (i.e. thermistor) without adding any additional components for temperature transduction. Si, a semiconductor, heats up when an electrical current pass.....
Document: NA amplification reactions require maintaining the sample at a temperature setpoint with high °precision. For PCR, the duration of each heating step must also be carefully controlled. Because the TriSilix uses Si, the substrate itself can be used both as an electrical heater and temperature sensor (i.e. thermistor) without adding any additional components for temperature transduction. Si, a semiconductor, heats up when an electrical current passes through it (known as Joule heating).
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