Author: Alejandro A Schäffer; Eneida Hatcher; Linda Yankie; Lara Shonkwiler; J Rodney Brister; Ilene Karsch-Mizrachi; Eric P Nawrocki
Title: VADR: validation and annotation of virus sequence submissions to GenBank Document date: 2019_11_22
ID: besvz92f_83
Snippet: Although VADR uses Infernal, a program capable of modelling RNA secondary structure, its models will not include structure information unless the user provides it as input to v-build.pl. For models without secondary structure it could be reasonably argued that VADR should use profile HMMs instead of CMs for the alignment stage, because HMMs are more efficient to compute with than CMs and in the absence of This article is a US Government work. It .....
Document: Although VADR uses Infernal, a program capable of modelling RNA secondary structure, its models will not include structure information unless the user provides it as input to v-build.pl. For models without secondary structure it could be reasonably argued that VADR should use profile HMMs instead of CMs for the alignment stage, because HMMs are more efficient to compute with than CMs and in the absence of This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license.
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