Author: Qu, Jie-Ming; Cao, Bin; Chen, Rong-Chang
Title: Chapter 2 Pathogenesis of COVID-19 Cord-id: 4oitd0md Document date: 2021_12_31
ID: 4oitd0md
Snippet: Combined with clinical manifestations and chest imaging features, such as dry cough and abnormal coagulation function, chest imaging mainly showed multiple small patches and interstitial changes at the early stage, with obvious extravasation and less exudative lesions, which developed into multiple ground-glass opacity and infiltrating shadows in the lungs. In critically ill patients receiving tracheal intubation, infiltration fluid is rare in the trachea, which is different from influenza and a
Document: Combined with clinical manifestations and chest imaging features, such as dry cough and abnormal coagulation function, chest imaging mainly showed multiple small patches and interstitial changes at the early stage, with obvious extravasation and less exudative lesions, which developed into multiple ground-glass opacity and infiltrating shadows in the lungs. In critically ill patients receiving tracheal intubation, infiltration fluid is rare in the trachea, which is different from influenza and avian influenza. We assume that pathogenesis of COVID-19 lung injury could mainly be impairment of the lung interstitium and vascular endothelium. Although ARDS can be found in some patients, exudative lesions are relatively less.
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