Author: Der-Nigoghossian, Caroline; Ciolek, Alana; Chuich, Taylor
Title: Therapeutic Approach to Coronavirus Disease Cord-id: 9w9hp35d Document date: 2020_10_6
ID: 9w9hp35d
Snippet: The global pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), was first identified in Wuhan, China, in December 2019. The viral genome was rapidly identified in order to develop diagnostic testing and therapeutic options. SARS-CoV2 is a single-stranded RNA-enveloped virus that uses its surface spike (S) protein to bind host cell’s angiotensin converting enzyme 2 (ACE2) receptor in the presence of host cell protease TMPRSS
Document: The global pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), was first identified in Wuhan, China, in December 2019. The viral genome was rapidly identified in order to develop diagnostic testing and therapeutic options. SARS-CoV2 is a single-stranded RNA-enveloped virus that uses its surface spike (S) protein to bind host cell’s angiotensin converting enzyme 2 (ACE2) receptor in the presence of host cell protease TMPRSS2, a cofactor for virus entry [1]. The virus uses RNA-dependent RNA polymerase to synthesize RNA leading to viral assembly and exocytosis [2].
Search related documents:
Co phrase search for related documents- action mechanism and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- action mechanism and additional research: 1, 2, 3
- action mechanism and adenosine nucleotide: 1, 2
- action mechanism and adjunctive therapy: 1, 2
- action mechanism and loading dose: 1, 2
- action mechanism and lopinavir ritonavir: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- action mechanism and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- action mechanism and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29
- activate cell and acute ards respiratory distress syndrome: 1
- activate cell and acute kidney injury: 1
- activate cell and acute kidney injury respiratory failure: 1
- activate cell and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- activate cell and lopinavir ritonavir: 1
- activate cell and lung disease: 1, 2
- activate cell and lung injury: 1
Co phrase search for related documents, hyperlinks ordered by date