Selected article for: "bind surface and host receptor"
Author: Rajarshi, Keshav; Chatterjee, Aroni; Ray, Shashikant
Title: Combating COVID-19 with Mesenchymal Stem Cell therapy
  • Cord-id: 9u2rk376
  • Document date: 2020_5_14
    • ID: 9u2rk376
    Snippet: The COVID-19 disease is caused by a positive stranded RNA virus called SARS-CoV-2. The virus mainly targets the pulmonary epithelial cells as it’s initial site of infection by letting its surface spike protein interact and bind to the host ACE2 receptor. The internalization and gradual replication of the virus results in an exaggerated immune response triggering release of many pro-inflammatory cytokines and chemokines. This immune storm is responsible for multiple health hazards in the host u
    Document: The COVID-19 disease is caused by a positive stranded RNA virus called SARS-CoV-2. The virus mainly targets the pulmonary epithelial cells as it’s initial site of infection by letting its surface spike protein interact and bind to the host ACE2 receptor. The internalization and gradual replication of the virus results in an exaggerated immune response triggering release of many pro-inflammatory cytokines and chemokines. This immune storm is responsible for multiple health hazards in the host ultimately leading to multiple organ failure. Mesenchymal stem cell therapy offers a promising approach towards mitigating the delirious effects of the infection in the COVID-19 patients. This therapy has shown to reduce the expression of pro-inflammatory cytokines as well as repair of damaged tissues in COVID-19 patients. This review has been organized to put forward the positive aruments and implications in support of mesenchymal stem cell therapy as a necessary approach for treating COVID-19 patients.

    Search related documents:
    Co phrase search for related documents
    • accurate prognosis and acute respiratory distress: 1
    • accurate prognosis and acute respiratory distress syndrome: 1
    • accurate prognosis and acute respiratory syndrome: 1, 2
    • activate immune system and acute respiratory: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • activate immune system and acute respiratory distress: 1, 2
    • activate immune system and acute respiratory distress syndrome: 1, 2
    • activate immune system and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • activate immune system and lung environment: 1
    • acute inflammatory pneumonia and lung result: 1
    • acute respiratory and adipose tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute respiratory and lung bacterial sepsis: 1
    • acute respiratory and lung environment: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • acute respiratory and lung result: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute respiratory distress and adipose tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • acute respiratory distress and lung environment: 1, 2, 3, 4, 5
    • acute respiratory distress and lung result: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
    • acute respiratory distress syndrome and adipose tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • acute respiratory distress syndrome and lung environment: 1, 2, 3, 4, 5
    • acute respiratory distress syndrome and lung result: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17