Selected article for: "acute respiratory syndrome and adaptive therapy"
Author: D’Abramo, Alessandra; Vita, Serena; Maffongelli, Gaetano; Mariano, Andrea; Agrati, Chiara; Castilletti, Concetta; Goletti, Delia; Ippolito, Giuseppe; Nicastri, Emanuele
Title: Prolonged and severe SARS-CoV-2 infection in patients under B-cell-depleting drug successfully treated: a tailored approach
  • Cord-id: bo88vjes
  • Document date: 2021_4_24
    • ID: bo88vjes
    Snippet: Prolonged B-cell depletion due to anti-CD20 monoclonal antibody (mAbs) therapy impairs the adaptive immune response causing severe manifestations during COronaVIrus Disease-2019. The cases of two patients under anti-CD20 therapy who experienced prolonged and severe COVID-19 successfully treated with mAbs against Severe Acute Respiratory Syndrome-CoV-2 spike proteins were reported.
    Document: Prolonged B-cell depletion due to anti-CD20 monoclonal antibody (mAbs) therapy impairs the adaptive immune response causing severe manifestations during COronaVIrus Disease-2019. The cases of two patients under anti-CD20 therapy who experienced prolonged and severe COVID-19 successfully treated with mAbs against Severe Acute Respiratory Syndrome-CoV-2 spike proteins were reported.

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