Pressure-Regulated Ventilator Splitting (PReVentS): A COVID-19 Response Paradigm from Yale University

Micha Sam Brickman Raredon; Clark Fisher; Paul Heerdt; Ranjit Deshpande; Steven Nivison; Elaine Fajardo; Shamsuddin Akhtar; Thomas Raredon; Laura E. Niklason

1. Shared ventilator -Measures and displays sum of patient tidal volumes (VTe), summed minute ventilation (Ve), and volume delivered by ventilator with each breath (Vdel). Additionally, it can identify certain disconnects and occlusions. We believe that a carefully set VTe alarm can identify most situations that require provider attention with good sensitivity and specificity (see below and Appendix S1). Furthermore, in the absence of superior alternatives, individual patient tidal volumes can be measured with the shared ventilator by briefly occluding the other patient's circuit (which puts the occluded patient into an expiratory hold). If measuring independent patient VTe in this manner, be sure to note that many ventilators adjust this measurement for the circuit compliance. Therefore, tidal . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.