Author: Patricia Rios; Amruta Radhakrishnan; Sonia M. Thomas; Nazia Darvesh; Sharon E. Straus; Andrea C. Tricco
Title: Preventing respiratory illness in older adults aged 60 years and above living in long-term care: A rapid overview of reviews Document date: 2020_3_26
ID: iuu8vmwy_45
Snippet: Managing respiratory illness in long-term care facilities: Statistically significant results were found from one moderate and one high quality systematic review for the use of amantadine as antiviral chemoprophylaxis for individuals diagnosed with lab-confirmed influenza (Table 1 ). In addition, statistically significant results were found from one high quality systematic review for the use of amantadine plus personal protective equipment to prev.....
Document: Managing respiratory illness in long-term care facilities: Statistically significant results were found from one moderate and one high quality systematic review for the use of amantadine as antiviral chemoprophylaxis for individuals diagnosed with lab-confirmed influenza (Table 1 ). In addition, statistically significant results were found from one high quality systematic review for the use of amantadine plus personal protective equipment to prevent spread of infection from individuals diagnosed with lab-confirmed influenza. Statistically significant results were not observed in one moderate and one high quality systematic review regarding rimantadine or neuraminidase inhibitors as antiviral chemoprophylaxis. However, statistically significant results were observed in one low quality systematic review for rimantadine as antiviral chemoprophylaxis. Mixed evidence was identified from two low quality systematic reviews for zanamivir as antiviral chemoprophylaxis that reported non-statistically significant reductions in viral respiratory infection rates. The full systematic review results are available in Appendix 5.
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