Author: Juri Dimaschko; Victor Podolsky
Title: VIRAL MUTATIONS AS A POSSIBLE MECHANISM OF HIDDEN IMMUNIZATION AND CONTAINMENT OF A PANDEMIA Document date: 2020_4_14
ID: fukn227t_113
Snippet: It is convenient to explore the role of mutation factor m in the absence of immunity (γ = 0, R = 0). We choose a unit of time so that β = 1. Then the SIMR model turns into an exactly solvable three-component SIM model These examples show how the epidemic outcome changes with increasing mutation parameter m. Note that the found relation (A8) holds for any monotonic dependence β(t) corresponding to a change in the transmission rate β during the.....
Document: It is convenient to explore the role of mutation factor m in the absence of immunity (γ = 0, R = 0). We choose a unit of time so that β = 1. Then the SIMR model turns into an exactly solvable three-component SIM model These examples show how the epidemic outcome changes with increasing mutation parameter m. Note that the found relation (A8) holds for any monotonic dependence β(t) corresponding to a change in the transmission rate β during the course of the epidemic due to quarantine restrictions. The only condition is the fulfilment of the relation r = (1 − m) β/γ 1, which allows neglecting the immunity factor γ, as done in equations (A1-A3).
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