Author: Moro, E.; Priori, A.; Beghi, E.; Helbok, R.; Campiglio, L.; Bassetti, C.L.; Bianchi, E.; Maia, L.F.; Ozturk, S.; Cavallieri, F.; Zedde, M.; Sellner, J.; Bereczki, D.; Rakusa, M.; Di Liberto, G.; Sauerbier, A.; Pisani, A.; Macerollo, A.; Soffietti, R.; Taba, P.; Crean, M.; Twardzik, A.; Orejaâ€Guevara, C.; Bodini, B.; Jenkins, T.J.; von Oertzen, T.J.
Title: The international EAN survey on neurological symptoms in patients with COVIDâ€19 infection Cord-id: kanm3n1u Document date: 2020_6_17
ID: kanm3n1u
Snippet: BACKGROUND AND PURPOSE: Although the main clinical features of COVIDâ€19 infection are pulmonary, several associated neurological signs, symptoms and diseases are emerging. Incidence and characteristics of neurological complications are unclear. For this reason, the European Academy of Neurology (EAN) core COVIDâ€19 Task Force initiated a survey on neurological symptoms observed in patients with COVIDâ€19 infection. METHODS: A 17â€question onâ€line survey was made available on the EAN websi
Document: BACKGROUND AND PURPOSE: Although the main clinical features of COVIDâ€19 infection are pulmonary, several associated neurological signs, symptoms and diseases are emerging. Incidence and characteristics of neurological complications are unclear. For this reason, the European Academy of Neurology (EAN) core COVIDâ€19 Task Force initiated a survey on neurological symptoms observed in patients with COVIDâ€19 infection. METHODS: A 17â€question onâ€line survey was made available on the EAN website and distributed to EAN members and other worldwide physicians starting on April 9(th), 2020. RESULTS: By April 27(th,) 2020, proper data were collected from 2,343 responders (out of 4,199), of whom 82.0% were neurologists, mostly from Europe. Most responders (74.7%) consulted patients with COVIDâ€19 mainly in emergency rooms and in COVIDâ€19 units. The majority (67.0%) had evaluated fewer than 10 patients with neurological manifestations of COVIDâ€19 (neuro COVIDâ€19). The most frequently reported neurological findings were headache (61.9%), myalgia (50.4%), anosmia (49.2%), ageusia (39.8%), impaired consciousness (29.3%), and psychomotor agitation (26.7%). Encephalopathy and acute cerebrovascular disorders were reported at 21.0%. Neurological manifestations were generally interpreted as being possibly related to COVIDâ€19, they were most commonly recognized in patients with multiple general symptoms, and occurred at any time during infection. CONCLUSION: Neurologists are currently and actively involved in the management of neurological issues related to the COVIDâ€19 pandemic. This survey justifies setting up a prospective registry to better capture the prevalence of patients with neuro COVIDâ€19, neurological disease characteristics and the contribution of neurological manifestations to outcome.
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