Selected article for: "pre fusion conformation and SARS spike protein"
Author: Ivan Mercurio; Vincenzo Tragni; Francesco Busco; Anna De Grassi; Ciro Leonardo Pierri
Title: Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies
  • Document date: 2020_4_18
    • ID: mswmkgl4_29
    Snippet: It was possible to superimpose the crystallized SARS-CoV-2 spike protein in pre-fusion conformation and the modelled SARS-CoV-2 spike protein trimers in post-fusion conformation for showing the deep conformational changes occurring along conformation interconversion (Fig. 4) . Apparently, the post-fusion conformation appears to be elongated and narrower than the pre-fusion conformation......
    Document: It was possible to superimpose the crystallized SARS-CoV-2 spike protein in pre-fusion conformation and the modelled SARS-CoV-2 spike protein trimers in post-fusion conformation for showing the deep conformational changes occurring along conformation interconversion (Fig. 4) . Apparently, the post-fusion conformation appears to be elongated and narrower than the pre-fusion conformation.

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