Author: Chang, Arthur J; Croix, Michael; Kenney, Patrick; Baron, Sarah; Hicar, Mark D
Title: SERUM RESPONSES OF CHILDREN WITH KAWASAKI DISEASE AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 PROTEINS. Cord-id: ofz11on5 Document date: 2020_8_12
ID: ofz11on5
Snippet: With recent reports showing clinical and laboratory overlap of multisystem inflammatory syndrome in children and Kawasaki disease (KD), we addressed the hypothesis that cross coronavirus humoral immunity leads to a parallel postinfectious phenomenon explaining similar pathologic findings in KD and multisystem inflammatory syndrome in children. We demonstrated no cross-reactivity in children with KD but observed some nonspecific interactions postintravenous immunoglobulin infusion.
Document: With recent reports showing clinical and laboratory overlap of multisystem inflammatory syndrome in children and Kawasaki disease (KD), we addressed the hypothesis that cross coronavirus humoral immunity leads to a parallel postinfectious phenomenon explaining similar pathologic findings in KD and multisystem inflammatory syndrome in children. We demonstrated no cross-reactivity in children with KD but observed some nonspecific interactions postintravenous immunoglobulin infusion.
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