Author: James Bull; Scott L. Nuismer; Rustom Antia
Title: Recombinant vector vaccines and within-host evolution Document date: 2019_2_8
ID: 3vssgben_30
Snippet: The results above suggest that vaccine evolution is only likely to compromise immunity to the antigen if 314 there is substantial evolution and this evolution results in more rapid clearance of the vaccine virus. In this 315 case, one possible solution takes advantage of the short-term nature of vaccine growth: control the inoculum......
Document: The results above suggest that vaccine evolution is only likely to compromise immunity to the antigen if 314 there is substantial evolution and this evolution results in more rapid clearance of the vaccine virus. In this 315 case, one possible solution takes advantage of the short-term nature of vaccine growth: control the inoculum.
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