Author: Linlin Zhang; Daizong Lin; Yuri Kusov; Yong Nian; Qingjun Ma; Jiang Wang; Albrecht von Brunn; Pieter Leyssen; Kristina Lanko; Johan Neyts; Adriaan de Wilde; Eric J. Snijder; Hong Liu; Rolf Hilgenfeld
Title: Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication Document date: 2020_2_10
ID: 7n8p9okf_7
Snippet: The inhibitory potencies of candidate a-ketoamides were evaluated against purified recombinant SARS-CoV M pro , HCoV-NL63 M pro , CVB3 3C pro , and EV-A71 3C pro . The most potent compounds were further tested against viral replicons and against SARS-CoV, MERS-CoV, or a whole range of enteroviruses in cell culture-based assays (Tables 1 -3 and Supplementary Table 1.....
Document: The inhibitory potencies of candidate a-ketoamides were evaluated against purified recombinant SARS-CoV M pro , HCoV-NL63 M pro , CVB3 3C pro , and EV-A71 3C pro . The most potent compounds were further tested against viral replicons and against SARS-CoV, MERS-CoV, or a whole range of enteroviruses in cell culture-based assays (Tables 1 -3 and Supplementary Table 1
Search related documents:
Co phrase search for related documents- cell culture and Supplementary table: 1, 2
- cell culture and viral replicon: 1, 2, 3, 4, 5
- inhibitory potency and potent compound: 1
Co phrase search for related documents, hyperlinks ordered by date