Author: Chang Ha Woo; Sungho Jang; Giyoung Shin; Gyoo Yeol Jung; Jeong Wook Lee
Title: Sensitive one-step isothermal detection of pathogen-derived RNAs Document date: 2020_3_9
ID: 1uqjmeic_6
Snippet: Two single-stranded DNA probes were designed to include several functional parts 83 involved in amplification, detection, and signal generation, thereby eliminating the need for 84 human intervention during the entire diagnostic process (Fig. 1) using the full-length, ligated probe as a DNA template, which can be bound with the 101 fluorogenic dye to emit fluorescence as an output (Fig. 1) . Notably, the reaction scheme of 102 SENSR inherently su.....
Document: Two single-stranded DNA probes were designed to include several functional parts 83 involved in amplification, detection, and signal generation, thereby eliminating the need for 84 human intervention during the entire diagnostic process (Fig. 1) using the full-length, ligated probe as a DNA template, which can be bound with the 101 fluorogenic dye to emit fluorescence as an output (Fig. 1) . Notably, the reaction scheme of 102 SENSR inherently supports two mechanisms that could amplify the signal: 1) multiple 103 All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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