Author: Jacob Kames; David Dillon Holcomb; Ofer Kimchi; Michael DiCuccio; Nobuko Hamasaki-Katagiri; Tony Wang; Anton A Komar; Aikaterini Alexaki; Chava Kimchi-Sarfaty
Title: Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design Document date: 2020_3_31
ID: 2fn25l6m_21
Snippet: A number of parameters were considered in determining which proteins could be targets for codon pair deoptimization. It has been shown that deoptimizing one third or less of the virus is sufficient to attenuate the virus, and more extensive deoptimization may lead to a completely inactive virus [40] ......
Document: A number of parameters were considered in determining which proteins could be targets for codon pair deoptimization. It has been shown that deoptimizing one third or less of the virus is sufficient to attenuate the virus, and more extensive deoptimization may lead to a completely inactive virus [40] .
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