Author: Corey T Watson; Karyn Meltz Steinberg; Tina A Graves-Lindsay; Rene L Warren; Maika Malig; Jacqueline E Schein; Richard K Wilson; Rob Holt; Evan Eichler; Felix Breden
Title: Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity Document date: 2014_7_3
ID: 62gfisc6_40
Snippet: IGK-proximal/distal, accession NG_000834.1/NG_000833.1). The outputs for each comparison were visually inspected for potential regions of structural variation. Putative breakpoints for the single variant identified were determined by creating a multi-sequence alignment using sequences from the IGL Kawasaki haplotype and novel BAC clone that spanned the regions of the predicted variant-associated breakpoints. Multi-sequence alignments were generat.....
Document: IGK-proximal/distal, accession NG_000834.1/NG_000833.1). The outputs for each comparison were visually inspected for potential regions of structural variation. Putative breakpoints for the single variant identified were determined by creating a multi-sequence alignment using sequences from the IGL Kawasaki haplotype and novel BAC clone that spanned the regions of the predicted variant-associated breakpoints. Multi-sequence alignments were generated and visualized in SeqMan Pro. Gene prediction was carried out using Genscan (genes.mit.edu/GENSCAN.html; 57 ), following by BLAST using the non-redundant gene database.
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