Author: Quast, Isaak; Tarlinton, David
Title: B cell memory: Understanding COVID-19 Cord-id: cmi404b7 Document date: 2021_1_23
ID: cmi404b7
Snippet: Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defence strategy and underlie virtually all vaccine success. Here we explain how B cells memory is generated by infection and vaccination, what influences its efficacy and its persistence and how characterising these parameters in the immune response to SARS-CoV-2 will help achieve protective immunity through vaccination.
Document: Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defence strategy and underlie virtually all vaccine success. Here we explain how B cells memory is generated by infection and vaccination, what influences its efficacy and its persistence and how characterising these parameters in the immune response to SARS-CoV-2 will help achieve protective immunity through vaccination.
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