Selected article for: "Benjamini Hochberg correction and false discovery rate"
Author: Allen Wang; Joshua A Chiou; Olivier B Poirion; Justin Buchanan; Michael J Valdez; Jamie M Verheyden; Xiaomeng Hou; Minzhe Guo; Jacklyn M Newsome; Parul Kudtarkar; Dina A Faddah; Kai Zhang; Randee E Young; Justinn Barr; Ravi Misra; Heidie Huyck; Lisa Rogers; Cory Poole; Jeffery A Whitsett; Gloria Pryhuber; Yan Xu; Kyle J Gaulton; Sebastian Preissl; Xin Sun
Title: Single Nucleus Multiomic Profiling Reveals Age-Dynamic Regulation of Host Genes Associated with SARS-CoV-2 Infection
  • Document date: 2020_4_14
    • ID: 5kvq6jtx_66
    Snippet: We then defined the promoter regions of ACE2, TMPRSS2, FURIN, BSG, and CTSL as 847 transcriptional start site (TSS) +/-1 kb and selected the sites co-accessible with each of 848 the promoters (co-accessibility score >0.05). Finally, we merged the elements co-849 accessible with the gene promoters from both analyses to generate a union set of 850 candidate elements. The copyright holder for this preprint (which was not peer-reviewed) is the . http.....
    Document: We then defined the promoter regions of ACE2, TMPRSS2, FURIN, BSG, and CTSL as 847 transcriptional start site (TSS) +/-1 kb and selected the sites co-accessible with each of 848 the promoters (co-accessibility score >0.05). Finally, we merged the elements co-849 accessible with the gene promoters from both analyses to generate a union set of 850 candidate elements. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.12.037580 doi: bioRxiv preprint Dataset ID and sex were used as technical covariates. Sites with False Discovery Rate 857 (FDR) < 0.05 after Benjamini-Hochberg correction were considered significant. Next, we 858 performed K-means using the relative accessibility score with a loci x timepoints matrix. 859

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