Author: Jieyu Guo; Xiangxiang Wei; Qinhan Li; Liliang Li; Zhaohua Yang; Yu Shi; Yue Qin; Xinyue Zhang; Xinhong Wang; Xiuling Zhi; Dan Meng
Title: Single-cell RNA Analysis on ACE2 Expression Provides Insight into SARS-CoV-2 Blood Entry and Heart Injury Document date: 2020_4_4
ID: in3b1nzv_21
Snippet: Urine is also directly filtered from blood. Therefore, the blood entry of SARS-CoV-2 is a pivotal step for its spread to other organs, body fluids and excreta, but how this virus enters bloodstream has not been fully elucidated. ACE2 was shown to be a receptor for SARS-CoV-2, whose expression pattern might provide possible routes for SARS-CoV-2 entry. In the present study, we demonstrated that ACE2 was mainly expressed in arterial vascular cells .....
Document: Urine is also directly filtered from blood. Therefore, the blood entry of SARS-CoV-2 is a pivotal step for its spread to other organs, body fluids and excreta, but how this virus enters bloodstream has not been fully elucidated. ACE2 was shown to be a receptor for SARS-CoV-2, whose expression pattern might provide possible routes for SARS-CoV-2 entry. In the present study, we demonstrated that ACE2 was mainly expressed in arterial vascular cells in fibrotic lungs, which might cause blood transmission of SARS-CoV-2. Patients with COPD bear a high mortality rate after being infected with SARS-All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
Search related documents:
Co phrase search for related documents- blood filter and body fluid: 1
- blood transmission and body fluid: 1
- blood transmission and mortality rate: 1, 2
- copd patient and expression pattern: 1
- copd patient and mortality rate: 1
- expression pattern and mortality rate: 1, 2
- high mortality rate and mortality rate: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date