Author: Bikash K. Bhandari; Paul P. Gardner; Chun Shen Lim
Title: Solubility-Weighted Index: fast and accurate prediction of protein solubility Document date: 2020_2_16
ID: 2rpr7aph_33
Snippet: To examine the enrichment of amino acid residues in soluble and insoluble proteins, we compute the bit scores for each amino acid residue in the PSI:Biology soluble and insoluble groups ( Supplementary Fig S7A) , we normalised the count of each residue in each x) ( group by the total number of residues in that group. We used the normalised count of amino acid residues using the eSOL E. coli sequences as the background. The bit score of residue fo.....
Document: To examine the enrichment of amino acid residues in soluble and insoluble proteins, we compute the bit scores for each amino acid residue in the PSI:Biology soluble and insoluble groups ( Supplementary Fig S7A) , we normalised the count of each residue in each x) ( group by the total number of residues in that group. We used the normalised count of amino acid residues using the eSOL E. coli sequences as the background. The bit score of residue for soluble or insoluble group is then given by the following equation:
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