Selected article for: "basic reproductive number and outbreak control"

Author: Jonathan Dushoff; Sang Woo Park
Title: Speed and strength of an epidemic intervention
  • Document date: 2020_3_3
  • ID: fhqbw32a_37
    Snippet: To illustrate this idea, we used simple assumptions to explore the effects of two HIV intervention strategies (condoms and test-and-treat), using both strength-and speed-based frameworks. In particular, we provided an alternative explanation for the result of Eaton and Hallett (2014) who used detailed mathematical modeling of HIV transmission to show that the amount of early transmission does not affect the effectiveness of the ART: we can contro.....
    Document: To illustrate this idea, we used simple assumptions to explore the effects of two HIV intervention strategies (condoms and test-and-treat), using both strength-and speed-based frameworks. In particular, we provided an alternative explanation for the result of Eaton and Hallett (2014) who used detailed mathematical modeling of HIV transmission to show that the amount of early transmission does not affect the effectiveness of the ART: we can control an outbreak if we can identify infected individuals and enroll them on ART faster than the observed rate at which new cases are generated, which does not depend on the estimates of the amount of early transmission. The original explanation of the result relied on a strength-based argument: increasing the amount of early transmission decreases the basic reproductive number, which negatively correlates with the outcome of the ART intervention (Eaton and Hallett, 2014) .

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