Author: Valley-Omar, Z.; Marais, K.; Iranzadeh, A.; Naidoo, M.; Korsman, S.; Maponga, T.; Hussey, H.; Davies, M.-A.; Boulle, A.; Doolabh, D.; Laubscher, M.; Deetlefs, J.; Maritz, J.; Scott, L.; Msomi, N.; Tegally, H.; de Oliveira, T.; Bhiman, J.; Williamson, C.; Preiser, W.; Hardie, D. R.; Hsiao, N.-y.
Title: Reduced amplification efficiency of the RNA-dependent-RNA-polymerase (RdRp) target enables tracking of the Delta SARS-CoV-2 variant using routine diagnostic tests Cord-id: b1q6zt0o Document date: 2021_10_1
ID: b1q6zt0o
Snippet: Routine SARS-CoV-2 surveillance in the Western Cape region of South Africa (January-August 2021) found a reduced PCR amplification efficiency of the RdRp gene target of the Seegene, Allplex 2019-nCoV diagnostic assay when detecting the Delta variant. We propose that this can be used as a surrogate for variant detection.
Document: Routine SARS-CoV-2 surveillance in the Western Cape region of South Africa (January-August 2021) found a reduced PCR amplification efficiency of the RdRp gene target of the Seegene, Allplex 2019-nCoV diagnostic assay when detecting the Delta variant. We propose that this can be used as a surrogate for variant detection.
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