Author: Renhong Yan; Yuanyuan Zhang; Yingying Guo; Lu Xia; Qiang Zhou
Title: Structural basis for the recognition of the 2019-nCoV by human ACE2 Document date: 2020_2_20
ID: elo7kfun_3
Snippet: ACE2 has also been suggested to be the receptor for the 2019-nCoV (3, 4) . The ectodomain of the 2019-nCoV S protein was reported to bind to the PD of ACE2 with a Kd of ~ 15 nM, measured with surface plasmon resonance (SPR) (5) . Docking analysis based on our structure of the ACE2-B 0 AT1 complex suggests that RBD can access to the PD, which protrudes into the extracellular space, in the presence of B 0 AT1, indicating compatibility of all three .....
Document: ACE2 has also been suggested to be the receptor for the 2019-nCoV (3, 4) . The ectodomain of the 2019-nCoV S protein was reported to bind to the PD of ACE2 with a Kd of ~ 15 nM, measured with surface plasmon resonance (SPR) (5) . Docking analysis based on our structure of the ACE2-B 0 AT1 complex suggests that RBD can access to the PD, which protrudes into the extracellular space, in the presence of B 0 AT1, indicating compatibility of all three proteins for ternary complex formation (1).
Search related documents:
Co phrase search for related documents- analysis docking and extracellular space: 1
- analysis docking and plasmon resonance: 1, 2, 3, 4, 5, 6
- analysis docking and SPR surface plasmon resonance: 1, 2
- analysis docking and surface plasmon resonance: 1, 2, 3, 4, 5, 6
- complex formation and plasmon resonance: 1, 2
- complex formation and surface plasmon resonance: 1, 2
- complex formation and ternary complex formation: 1, 2, 3, 4, 5, 6
- complex formation and ternary complex formation protein: 1
- plasmon resonance and SPR surface plasmon resonance: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- plasmon resonance and SPR surface plasmon resonance measure: 1, 2, 3
- plasmon resonance and surface plasmon resonance: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76
- SPR surface plasmon resonance and surface plasmon resonance: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- SPR surface plasmon resonance measure and surface plasmon resonance: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date