Author: Tavasolian, Fataneh; Hatam, Gholam Reza; Mosawi, Sayed Hussain; Saadi, Mahdiyar Iravani; Abdollahi, Elham; Jamialahmadi, Tannaz; Sathyapalan, Thozhukat; Sahebkar, Amirhossein
Title: The Immune Response and Effectiveness of COVID-19 Therapies. Cord-id: mneqztjs Document date: 2021_1_1
ID: mneqztjs
Snippet: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly pathogenic with relatively high mortality and morbidity. In addition to pneumonia, acute respiratory distress syndrome, and microembolic disorder, a high proportion of patients with SARS-CoV-2 develop lymphopenia and cytokine storm disorder. This review explores the underlying mechanisms behind the pathogenesis of SARS-CoV-2, especially the immune mechanisms, which could be potent
Document: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly pathogenic with relatively high mortality and morbidity. In addition to pneumonia, acute respiratory distress syndrome, and microembolic disorder, a high proportion of patients with SARS-CoV-2 develop lymphopenia and cytokine storm disorder. This review explores the underlying mechanisms behind the pathogenesis of SARS-CoV-2, especially the immune mechanisms, which could be potentially used as therapeutic targets for the management of COVID-19.
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