Selected article for: "human coronavirus and molecular detection"
Author: Srinivasan, Ashok; Flynn, Patricia; Gu, Zhengming; Hartford, Christine; Lovins, Richard; Sunkara, Anusha; Srivastava, Deo K.; Leung, Wing; Hayden, Randall T.
Title: Detection of Respiratory Viruses in Asymptomatic Children Undergoing Allogeneic Hematopoietic Cell Transplantation
  • Cord-id: j4qmvlzw
  • Document date: 2012_9_14
    • ID: j4qmvlzw
    Snippet: Detection of respiratory viruses by molecular methods, in children without respiratory symptoms undergoing hematopoietic cell transplantation (HCT), has not been well described. A prospective study of 33 asymptomatic children detected respiratory viruses in 8 of 33 (24%) patients before HCT. Human rhinovirus (HRV) was detected in 5 patients, and human adenovirus (hADV) in 3 patients. Two additional patients shed HRV, and one shed human coronavirus (hCoV), post-HCT. Two patients had co-infections
    Document: Detection of respiratory viruses by molecular methods, in children without respiratory symptoms undergoing hematopoietic cell transplantation (HCT), has not been well described. A prospective study of 33 asymptomatic children detected respiratory viruses in 8 of 33 (24%) patients before HCT. Human rhinovirus (HRV) was detected in 5 patients, and human adenovirus (hADV) in 3 patients. Two additional patients shed HRV, and one shed human coronavirus (hCoV), post-HCT. Two patients had co-infections. Of the 11 asymptomatic patients where respiratory virus was detected, 3 (27%) later developed an upper respiratory tract infection, from the same virus.

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