Selected article for: "animal model and SARS cov"

Author: Hualan Chen
Title: Susceptibility of ferrets, cats, dogs, and different domestic animals to SARS-coronavirus-2
  • Document date: 2020_3_31
  • ID: mo4luyx6_14
    Snippet: Ferrets have frequently been used as an animal model for the study of human respiratory viruses (20) (21) (22) (23) (24) (25) (26) . Unlike influenza viruses and other human SARS-coronavirus, which replicate in both the upper . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.30.015347 doi: bioRxiv preprin.....
    Document: Ferrets have frequently been used as an animal model for the study of human respiratory viruses (20) (21) (22) (23) (24) (25) (26) . Unlike influenza viruses and other human SARS-coronavirus, which replicate in both the upper . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.30.015347 doi: bioRxiv preprint and lower respiratory tract of ferrets (20, 22-24, 26, 27) , we found SARS-CoV-2 only replicates in the nasal turbinate, soft palate, and tonsils of ferrets. It may also replicate in the digestive tract, as viral RNA was detected in the rectal swabs of the virus-infected ferrets, but virus was not detected in lung lobes, even after the ferrets were intratracheally inoculated with the virus.

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