Selected article for: "antiviral agent and specific antiviral agent"
Author: Lei, L.; Qian, H.; Yang, X.; Zhou, X.; Zhang, X.; Zhang, D.; Dai, T.; Guo, R.; Shi, L.; Cheng, Y.; Zhang, B.; Hu, J. H.; Guo, Y.
Title: The phenotypic changes of γδ T cells in COVID-19 patients
  • Cord-id: 5ekdfers
  • Document date: 2020_4_7
    • ID: 5ekdfers
    Snippet: A novel pneumonia-associated respiratory syndrome named coronavirus disease-2019 (COVID-19), which caused by SARS-CoV-2 and broken in Wuhan, China in the end of 2019. Unfortunately, there is no specific antiviral agent or vaccine available to treat SARS-CoV-2 infections. Also, information regarding the immunological characteristics in COVID-19 patients remains limited. Here we collected the blood samples from 18 healthy donors (HD) and 38 COVID-19 patients to analyze changes in {gamma}{delta} T
    Document: A novel pneumonia-associated respiratory syndrome named coronavirus disease-2019 (COVID-19), which caused by SARS-CoV-2 and broken in Wuhan, China in the end of 2019. Unfortunately, there is no specific antiviral agent or vaccine available to treat SARS-CoV-2 infections. Also, information regarding the immunological characteristics in COVID-19 patients remains limited. Here we collected the blood samples from 18 healthy donors (HD) and 38 COVID-19 patients to analyze changes in {gamma}{delta} T cells. In comparison to HD, the {gamma}{delta} T cells percentage was decreased. {gamma}{delta} T cells are able to immediately respond to SARS-CoV-2 infection and upregulate the activation marker CD25. In addition, the increased expression of CD4 in {gamma}{delta} T cells may serve as a biomarker for the assessment of SARS-CoV-2 infection.

    Search related documents:
    Co phrase search for related documents
    • activation marker and adaptive immune cell: 1, 2
    • activation marker and adaptive innate: 1, 2
    • activation marker and adaptive innate immunity: 1
    • activation marker surface expression and acute hiv infection: 1
    • acute hiv infection and adaptive innate: 1
    • acute hiv infection and adaptive innate immunity: 1
    • adaptive innate and lung inflammatory response: 1, 2, 3