Author: Kotsias, Fiorella; Bucafusco, Danilo; Nuñez, Denise Anabel; Lago Borisovsky, LucÃa Antonella; Rodriguez, Mariana; Bratanich, Ana Cristina
Title: Genomic characterization of canine circovirus associated with fatal disease in dogs in South America Cord-id: ns6a7q0j Document date: 2019_6_25
ID: ns6a7q0j
Snippet: Canine circovirus (CanineCV) was detected, together with canine parvovirus (CPV), in samples from an outbreak of fatal gastroenteritis in dogs in Argentina. We obtained the full-length genome of this recently discovered virus by overlapping PCR, designated strain UBA-Baires. Sequence analysis revealed a highly conserved genome but also showed several unique mutations in amino acids from the capsid protein that have not been previously reported. Phylogenetic analysis shows that this strain is mor
Document: Canine circovirus (CanineCV) was detected, together with canine parvovirus (CPV), in samples from an outbreak of fatal gastroenteritis in dogs in Argentina. We obtained the full-length genome of this recently discovered virus by overlapping PCR, designated strain UBA-Baires. Sequence analysis revealed a highly conserved genome but also showed several unique mutations in amino acids from the capsid protein that have not been previously reported. Phylogenetic analysis shows that this strain is more closely related to European strains than to viruses detected in North America or Asia. Although the pathogenic role of CanineCV in dogs is still unclear, this study highlights the importance of CanineCV as a coinfecting virus in disease development. To our knowledge, this is the first report of the involvement of CanineCV in severe clinical disease in dogs in South America. Our results expand our information on the geographical extent of this virus and contribute to the understanding of its role in disease.
Search related documents:
Co phrase search for related documents- accession number and lymph node: 1, 2
- accession number and lymph node tissue: 1
Co phrase search for related documents, hyperlinks ordered by date