Etiopathogenetic therapy effect on the microcirculation of the bulbar conjunctiva in patients with dyslipidemia after covid-19 associated pneumonia

Kalyuzhnaya, E. N.; Ponomareva, M. N.; Petrov, I. M.; Karpova, D. A.; Gapon, L. I.; Petelina, T. I.; Yaroslavskaya, E. I.

Purpose: to study the hemodynamics of the bulbar conjunctiva in patients with dyslipidemia and a history of COVID-19 associated pneumonia who received etiopathogenetic therapy. Material and methods. 54 patients (108 eyes) aged 61 ± 14 with a documented diagnosis of COVID-19-associated pneumonia and dyslipidemia were prospectively examined 3 months after the discharge from hospital. Patients were divided into two groups, identical in gender and age, depending on the presence or absence of metabolic syndrome. For 1 month, both groups received etiotropic therapy: statins, antioxidants thioctic acid pills and topical antioxidant instillations (1 % solution of Emoxipine® three times a day, and instillations of NSAID Broxinac® (in the form of 0.09 % Bromfenacum eyedrops) 1 drop 2 times a day. Results. Improvement was achieved in perivascular parameters (of 54 % of patients of group 1 and 50 % of patients of group 2);in the shape of blood vessels (in 10 and 11 % of cases, respectively);intravascular parameters (in 71 and 78 %, respectively). Conclusion. The proposed etiopathogenetic therapy has a positive effect on the state of damaged bulbar conjunctiva microcirculation. © 2021, Real Time LLC. All rights reserved.